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Cagrilintide + Semaglutide
Cagrilintide + Semaglutide $252.00

Cagrilintide

Catalog No.

T76262

Purity:

99.95%

⭐️⭐️⭐️⭐️⭐️

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Cagrilintide is a long-acting amylin analogue acting as a dual agonist of the amylin receptor and calcitonin receptor, reducing body weight and food intake for obesity research.
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Price range: $154.00 through $308.00

With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Cagrilintide Common Questions

What’s pIC50?

pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).

What’s Kd?

Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.

Product Introduction

Bioactivity

Description

Cagrilintide is a long-acting amylin analogue acting as a dual agonist of the amylin receptor and calcitonin receptor, reducing body weight and food intake for obesity research.

In vitro

Cagrilintide (compound 23) (0.1, 1, 3, 10, and 30 nmol/kg, subcutaneous injection) reduced food intake in rats [2].
Cagrilintide (10 nmol/kg, administered intravenously or subcutaneously) exhibited favorable pharmacokinetic parameters [2].

Chemical Properties

Molecular Weight

4409.01

Formula

C194H312N54O59S2

Cas No.

1415456-99-3

Relative Density.

no data available

Sequence

{Eicosanedioic acid-γ-Glu}-Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Glu-Phe-Leu-Arg-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Pro-NH2 (Disulfide bridge:Cys3-Cys8)

Sequence Short

{Eicosanedioic acid-γ-Glu}-KCNTATCATQRLAEFLRHSSNNFGPILPPTNVGSNTP (Disulfide bridge:Cys3-Cys8)

Storage & Solubility Information

Storage

Shipping with blue ice/Shipping at ambient temperature.
Actual storage temperature shall be subject to the COA.

Formula

H2O: 80 mg/mL (18.14 mM), Sonication is recommended.🏅

Solution Preparation Table

DMSO

1mg

5mg

10mg

1 mM

0.2268 mL

1.1340 mL

2.2681 mL

11.3404 mL

5 mM

0.0454 mL

0.2268 mL

0.4536 mL

2.2681 mL

10 mM

0.0227 mL

0.1134 mL

0.2268 mL

1.1340 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

References