LIPO-C (NO B12)
LIPO-C (NO B12) is a lipotropic multi-component formulation designed for metabolic and lipid utilization research. It typically contains key lipotropic agents such as L-carnitine, methionine, inositol, and choline, without the inclusion of vitamin B12. This formulation supports fatty acid transport, promotes lipid metabolism, and facilitates energy production at the cellular level, making it suitable for studies where B12 exclusion is required.
$84.00
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
Questions
What’s pIC50?
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
What’s Kd?
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
Product Introduction
Bioactivity
Description
LIPO-C (NO B12) is a lipotropic multi-component formulation designed for metabolic and lipid utilization research. It typically contains key lipotropic agents such as L-carnitine, methionine, inositol, and choline, without the inclusion of vitamin B12. This formulation supports fatty acid transport, promotes lipid metabolism, and facilitates energy production at the cellular level, making it suitable for studies where B12 exclusion is required.
Targets & IC50
Targets:
Carnitine Palmitoyltransferase I (CPT1) (via L-carnitine-mediated fatty acid transport)
Fatty Acid Oxidation Pathway
Methylation Pathways
IC50:
Not applicable (multi-component formulation without a single defined inhibitory target)
In vitro
METHODS: HepG2 hepatocytes and 3T3-L1 adipocytes were treated with LIPO-C (NO B12) (0–100 μg/mL, component-adjusted concentrations) for 24–72 hours. Lipid metabolism, mitochondrial activity, and fatty acid oxidation were evaluated using enzymatic assays, Oil Red O staining, and Western blot analysis of metabolic markers.
RESULTS: LIPO-C (NO B12) enhances fatty acid oxidation and promotes lipid utilization in hepatocytes and adipocytes. It reduces intracellular lipid accumulation and increases mitochondrial metabolic activity. The formulation supports lipolysis and metabolic efficiency without affecting pathways associated with vitamin B12-dependent processes. No significant cytotoxicity is observed at standard experimental concentrations. [1]
Synonyms
LIPO-C (B12-free)
Chemical Properties
Molecular Weight
no data available
4813.45
Formula
no data available
Cas No.
no data available
Smiles
no data available
Relative Density.
no data available
Sequence
no data available
Sequence Short
no data available
Storage & Solubility Information
Storage
Formula
no data available