Acetic Acid Solution is an aqueous solution of acetic acid (CH₃COOH) commonly used in laboratory and research applications as a pH modifier, solvent, and buffering component. It is widely applied in peptide and protein research to enhance solubility, prevent aggregation, and maintain stability during preparation and storage. Acetic acid solutions are also used in biochemical assays and chromatographic processes.
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Questions
Acetic Acid Solution Common Questions
What’s pIC50?
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
What’s Kd?
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
Description
Acetic Acid Solution is an aqueous solution of acetic acid (CH₃COOH) commonly used in laboratory and research applications as a pH modifier, solvent, and buffering component. It is widely applied in peptide and protein research to enhance solubility, prevent aggregation, and maintain stability during preparation and storage. Acetic acid solutions are also used in biochemical assays and chromatographic processes.
Targets & IC50
Targets:
Acetic Acid
pH Regulation
IC50:
Not applicable (solution used as solvent/buffer, not an inhibitor)
In vitro
METHODS: Acetic Acid Solution (typically 0.1%–5%) was used to dissolve peptides and proteins prior to cell-based assays. Solubility, stability, and aggregation behavior were evaluated in standard in vitro systems.
RESULTS: Acetic Acid Solution improves solubility of hydrophobic and aggregation-prone peptides, enabling more consistent preparation and handling. It supports stable pH conditions and enhances reproducibility in biochemical experiments. When properly diluted, no significant cytotoxic effects are observed in downstream assays. [1]
Synonyms
CH₃COOH Solution
Molecular Weight
60.05 g/mol (acetic acid)
Formula
CH₃COOH (acetic acid component)
Cas No.
64-19-7 (acetic acid)
Smiles
CC(=O)O
Relative Density.
1.01–1.05 g/cm³ (depending on concentration)
Sequence
Not applicable
Sequence Short
N/A
Storage
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