PT-141
$98.00
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
Questions
PT-141 Common Questions
What’s pIC50?
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
What’s Kd?
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
Product Introduction
Bioactivity
Description
Synonyms
PT-141, PT141, PT 141
Chemical Properties
Molecular Weight
1025.16
Formula
C50H68N14O10
Cas No.
189691-06-3
Smiles
C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H](NC([C@H](CCCC)NC(C)=O)=O)CC(=O)NCCCC[C@@H](C(O)=O)NC3=O
Relative Density.
1.43 g/cm3
Sequence
Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys(1)-OH
Sequence Short
XDHFRWK
Storage & Solubility Information
Storage
Formula
References
- 1.Clayton AH, Althof SE, Kingsberg S, DeRogatis LR, Kroll R, Goldstein I, Kaminetsky J, Spana C, Lucas J, Jordan R, Portman DJ. Bremelanotide for female sexual dysfunctions in premenopausal women: a randomized, placebo-controlled dose-finding trial. Womens Health (Lond). 2016 Jun;12(3):325-37. doi: 10.2217/whe-2016-0018. Epub 2016 May 16. PubMed PMID: 27181790; PubMed Central PMCID: PMC5384512.
- 2.Seftel AD. Re: Bremelanotide for Female Sexual Dysfunctions in Premenopausal Women: A Randomized, Placebo-Controlled Dose-Finding Trial. J Urol. 2016 Nov;196(5):1516-1517. doi: 10.1016/j.juro.2016.08.063. Epub 2016 Aug 23. PubMed PMID: 27751477.
- 3.Safarinejad MR, Hosseini SY. Salvage of sildenafil failures with bremelanotide: a randomized, double-blind, placebo controlled study. J Urol. 2008 Mar;179(3):1066-71. doi: 10.1016/j.juro.2007.10.063. Epub 2008 Jan 18. PubMed PMID: 18206919.
- 4.Pfaus J, Giuliano F, Gelez H. Bremelanotide: an overview of preclinical CNS effects on female sexual function. J Sex Med. 2007 Nov;4 Suppl 4:269-79. PubMed PMID: 17958619.