Selank
Selank is a synthetic analog of tuftsin.
Price range: $70.00 through $126.00
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Questions
Selank Common Questions
What’s ED50?
Effective dose 50 (ED50）refers to the dose of a drug that produces a specific effect in 50% of the population that has been administered that dose.
What’s Kd?
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
Product Introduction
Bioactivity
Description
Selank is a synthetic analog of tuftsin.
Synonyms
TP-7, TP7, TP 7
Chemical Properties
Molecular Weight
751.87
Formula
C33H57N11O9
Cas No.
129954-34-3
Smiles
C(N[C@H](C(=O)N1[C@H](C(NCC(=O)N2[C@H](C(O)=O)CCC2)=O)CCC1)CCCNC(=N)N)(=O)[C@H]3N(C([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCCCN)=O)CCC3
Relative Density.
1.53 g/cm3 (Predicted)
Sequence
Thr-Lys-Pro-Arg-Pro-Gly-Pro
Sequence Short
TKPRPGP
Storage & Solubility Information
Storage
Shipping with blue ice/Shipping at ambient temperature.
Actual storage temperature shall be subject to the COA.
Formula
DMSO: Soluble🏅
References
- 1.Kolomin T, Morozova M, Volkova A, Shadrina M, Andreeva L, Slominsky P, Limborska S, Myasoedov N. The temporary dynamics of inflammation-related genes expression under tuftsin analog Selank action. Mol Immunol. 2014 Mar;58(1):50-5. doi: 10.1016/j.molimm.2013.11.002. Epub 2013 Nov 27. PubMed PMID: 24291245.
- 2.Volkova A, Shadrina M, Kolomin T, Andreeva L, Limborska S, Myasoedov N, Slominsky P. Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission. Front Pharmacol. 2016 Feb 18;7:31. doi: 10.3389/fphar.2016.00031. eCollection 2016. PubMed PMID: 26924987; PubMed Central PMCID: PMC4757669.
- 3.Medvedev VE, Tereshchenko ON, Kost NV, Ter-Israelyan AY, Gushanskaya EV, Chobanu IK, Sokolov OY, Myasoedov NF. [Optimization of the treatment of anxiety disorders with selank]. Zh Nevrol Psikhiatr Im S S Korsakova. 2015;115(6):33-40. doi: 10.17116/jnevro20151156133-40. Russian. PubMed PMID: 26356395.
- 4.Kolik LG, Nadorova AV, Kozlovskaya MM. Efficacy of peptide anxiolytic selank during modeling of withdrawal syndrome in rats with stable alcoholic motivation. Bull Exp Biol Med. 2014 May;157(1):52-5. doi: 10.1007/s10517-014-2490-4. Epub 2014 Jun 10. PubMed PMID: 24913576.