Semax
Price range: $84.00 through $133.00
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
Questions
Semax Common Questions
What’s pIC50?
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
What’s Kd?
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
Product Introduction
Bioactivity
Description
Semax is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.
Chemical Properties
Molecular Weight
813.93
Formula
C37H51N9O10S
Cas No.
80714-61-0
Smiles
C([C@H](CC1=CC=CC=C1)NC([C@H](CC2=CN=CN2)NC([C@@H](NC([C@H](CCSC)N)=O)CCC(O)=O)=O)=O)(=O)N3[C@H](C(NCC(=O)N4[C@H](C(O)=O)CCC4)=O)CCC3
Relative Density.
1.31g/cm3
Sequence
Met-Glu-His-Phe-Pro-Gly-Pro
Sequence Short
MEHFPGP
Storage & Solubility Information
Storage
Formula
References
- 1.Bashkatova, V.G., Koshelev, V.B., Fadyukova, O.E., et al. Novel synthetic analogue of ACTH 4-10 (Semax) but not glycine prevents the enhanced nitric oxide generation in cerebral cortex of rats with incomplete global ischemia. Brain Res. 894(1), 145-149 (2001).
- 2.Ivanova, D.M., Levitskaya, N.G., Andreeva, L.A., et al. Comparative study of analgesic potency of ACTH4-10 fragment and its analog semax. Bull. Exp. Biol. Med. 143(1), 5-8 (2007).
- 3.Volodina, M.A., Sebentsova, E.A., Glazova, N.Y., et al. Semax attenuates the influence of neonatal maternal deprivation on the behavior of adolescent white rats. Bull. Exp. Biol. Med. 152(5), 560-563 (2012).