Klow (TB10mg+BPC10mg+GHK50mg+KPV10mg)
TB + BPC + GHK Blend is a multi-peptide formulation combining Thymosin Beta (TB), BPC-157, and GHK (Glycyl-L-Histidyl-L-Lysine), designed for research on tissue repair, wound healing, and cellular regeneration. BPC-157 contributes to cytoprotection and vascular repair, TB peptides regulate cell migration and actin dynamics, while GHK is known for its role in tissue remodeling, collagen synthesis, and regenerative signaling. This combination is widely used to investigate synergistic effects in skin repair, soft tissue healing, and extracellular matrix regeneration.
$266.00
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
Questions
Klow Common Questions
What’s pIC50?
pIC50 is the negative log of the IC50 value when converted to molar.That is, pIC50=-log(IC50).
What’s Kd?
Dissociation consent (Kd) reflects the affinity of a compound for its target. In some cases, it can be equivalent to Ki.
Product Introduction
Bioactivity
Description
Klow TB + BPC + GHK + KPV Blend is a multi-peptide formulation combining Thymosin Beta (TB), BPC-157, GHK (Glycyl-L-Histidyl-L-Lysine), and KPV (Lys-Pro-Val), designed for research on tissue repair, inflammation modulation, and regenerative signaling. BPC-157 supports cytoprotection and vascular repair, TB peptides regulate cell migration and actin dynamics, GHK promotes collagen synthesis and extracellular matrix remodeling, while KPV is known for its anti-inflammatory and immunomodulatory properties. This combination is widely used to investigate synergistic effects in wound healing, tissue regeneration, and inflammation control.
Targets & IC50
Targets:
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Vascular Endothelial Growth Factor Receptor (VEGFR)
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Actin
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Extracellular Matrix Remodeling
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NF-κB Signaling Pathway
IC50:
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Not applicable (multi-peptide formulation; not characterized by inhibitory IC50 values)
In vitro
METHODS: Human dermal fibroblasts, endothelial cells, keratinocytes, and macrophage cell lines were treated with BPC-157 (0–10 μM), TB peptide (0–1 μM), GHK (0–50 μM), and KPV (0–100 μM), individually and in combination, for 24–96 hours. Cell proliferation, migration, collagen synthesis, and inflammatory marker expression were evaluated using wound healing assays, ELISA, and Western blot analysis.
RESULTS: The combination of TB, BPC-157, GHK, and KPV significantly enhances tissue repair processes while reducing inflammatory signaling. BPC-157 promotes vascular repair, TB peptides enhance cell migration and cytoskeletal remodeling, GHK stimulates collagen production and extracellular matrix regeneration, and KPV suppresses pro-inflammatory pathways such as NF-κB signaling. Together, they demonstrate strong synergistic effects in accelerating tissue regeneration and improving cellular repair with reduced inflammation. No significant cytotoxicity is observed at commonly used experimental concentrations. [1]
Synonyms
TB + BPC + GHK + KPV blend
Chemical Properties
Molecular Weight
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BPC-157: ~1419.6 Da
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TB peptide: ~4963 Da (variant-dependent)
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GHK: ~340.4 Da
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KPV: ~369.5 Da
Formula
Not applicable (multi-peptide formulation)
Cas No.
Not applicable (each component has individual CAS numbers)
Smiles
Not applicable (peptide mixture)
Relative Density.
no data available
Sequence
BPC-157: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Thymosin Beta (example TB4): Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
GHK: Gly-His-Lys
KPV: Lys-Pro-Val
Sequence Short
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BPC-157: 15 aa
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TB peptide: ~43 aa
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GHK: 3 aa
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KPV: 3 aa
Storage & Solubility Information
Storage